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Mirum Shares Surge More Than 90% in 6 Months: Here's Why
The company’s lead product is Livmarli (maralixibat), an orally administered ileal bile acid transporter (“IBAT”) inhibitor approved for the treatment of cholestatic pruritus in patients ...
Nature13d
Bile Acids And Cholestatic Liver Disease
Disrupted bile acid transport and homeostasis can lead to cholestatic disorders and contribute to a range of liver diseases, including nonalcoholic fatty liver disease and liver cancers[1].
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Progress in the management of patients with cholestatic liver disease: Where are we and where are we going?
OCA works by reducing bile acid synthesis and increasing bile acid transport from the liver. Fibrates: Bezafibrate and fenofibrate, as adjunctive therapies to UDCA, have demonstrated improved ...