Low-density lipoproteins (LDL)—commonly known as bad cholesterol—have long been on scientists' radar as a major contributor ...

Electron ‘shadows’ from thousands of individual LDL particles, each caught in random orientations, were then reassembled to create a 3D structure. Cryo-EM is transforming biomolecular ...

High pressure freezing offers versatile and deep capability in the study of intricate changes in fine structure or cellular dynamics ... workflows enabled by high pressure freezing on the EM ICE. - ...