They coined the term "receptor-mediated endocytosis" to describe the entry of LDL into the cells (Goldstein & Brown 2009). In another series of experiments, Brown and Goldstein used electron ...
Inhibition of AMPA receptor endocytosis could help treat addiction to heroin. Van den Oever et al. have used a rat model to demonstrate that the link between re-exposure to preconditioned stimuli ...
it sometimes requires an additional factor such as a protein that is a receptor for a specific chemical serving as a “named ticket to entry” into the cell. One can call its endocytosis that is ...
Revive Therapeutics (RVVTF) announced an update on the research study evaluating Bucillamine as a potential treatment for nerve agent exposure, ...
Reduced receptor-mediated LDL endocytosis causing raised blood LDL cholesterol (LDL-C) is the main defect, but other abnormalities due to lack of LDL receptors include altered hepatic cholesterol ...
The DRDC have the first set of animals (soman controls and bucillamine pretreated) completed and is now performing the assays looking at GABA receptor downregulation. Over the next few weeks data will ...
This arrangement enables efficient receptor-mediated endocytosis. Local refinements of cryo-EM data identified the apoB100 β-belt as a continuous amphipathic structure wrapped around LDL’s ...
One key process in maintaining this equilibrium is endocytosis, the mechanism by which membrane components are internalised. Organisms have evolved various endocytic pathways, all relying on ...