The validity as well as the usefulness of measuring components of the renin-angiotensin-aldosterone system in the diagnosis and treatment of patients with elevated blood pressure (BP) has been ...

block the effects of the renin enzyme, relaxing blood vessels and allowing blood to flow more easily. They are widely used as first-line medications for hypertension (high blood pressure).

We had at our disposal not only an enzyme assay but also a highly discriminatory ... on the physiological and clinical role of the renin–angiotensin system. The clinical studies with ACE ...

In a complicated system of feedback loops, the kidneys are able to detect a change in blood pressure, leading to a release of the enzyme renin. Renin converts the precursor angiotensinogen to ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

Lisinopril inhibits angiotensin-converting enzyme. It suppresses the renin-angiotensin-aldosterone system. The mechanism of the antihypertensive effect of thiazides is unknown. Fetal toxicity may ...