Lionel Messi is expected to play as Inter Miami faces Sporting San Miguelito in Panama City, Panama at 5 p.m. ET. Here's what you need to know.

With Neymar Jr.'s return to Santos FC, the Brazilian club is now aiming to challenge the top teams in Brazil. To bolster their squad, they have secured the signing of an Argentine player who was a former rival of Lionel Messi’s Inter Miami in Major League Soccer.

The preseason match, which kicks off at 5 p.m., is the third in the club’s Americas Tour, which also includes a game against Olimpia in Honduras next Saturday. Miami won its first two preseason games in penalty kick shootouts against Mexican team Club America and Universitario of Peru.

Lionel Messi and Inter Miami fell short of their goals in 2024, so the 2025 season will be all about redemption.

Lionel Messi has appeared strong and in prime form in Inter Miami’s first two preseason games of the year. He's expected to play Sunday in Panama.

Inter Miami put on a show in Panama and walked away with a comfortable 1–3 victory against Sporting San Miguelito.

Sporting San Miguelito take on Inter Miami in a 2025 friendly match. Here's all the key information you need, including the kickoff time and details on how to watch the game on TV or stream it in the United States.

Inter Miami, with goals from Cremaschi, Allende, and Picault, defeated Sporting San Miguelito 1-3 on Sunday in an international friendly match that marked the return of Argentine Lionel Messi to Panama,