AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve ...

Classically solved protein structures are chosen, and prediction tools are only given the amino acid sequences to work with.

The building blocks of proteins are amino acids, which are small organic molecules that consist of an alpha ... protein is typically the most energetically favorable one. As proteins fold ...

Along with greater accuracy for the prediction of 3D protein structures, it offers a big increase for antibody-antigen interactions and can decipher protein-ligand interactions that – according ...

PELSA has showed superior sensitivity in target protein identifications. For example, in identifying the target proteins of a pan-kinase inhibitor staurosporine, PELSA showed a 12-fold increase in ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...