The results have just been published in the journal Nucleic Acids Research, and were obtained using biochemical approaches and state-of-the-art cryo-electron microscopy provided by the Integrated ...

Pipeline for particle picking in cryo-electron microscopy images using convolutional neural networks trained from positive and unlabeled examples. Also featuring micrograph and tomogram denoising with ...

This represents how XLuminA explores vast experimental configurations to discover novel super-resolution microscopy techniques. The glowing paths highlight the system’s ability to find optimal routes ...

The present study employed advanced cryo-electron microscopy (cryo-EM) techniques to elucidate the interactions between apoB100, LDL, and the LDLR. Low-density lipoprotein particles were purified ...

Background: Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. Placenta-derived extracellular vesicles ...

ultrastructural analysis of cells and tissue The system is fully equipped with a cryostage and Gatan 16 megapixel camera for cyroEM and the MirrorCLEM software for correlative light electron ...

Feb. 23, 2023 — High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data. The visualization, analysis and dissemination ...

Unlike other methods to analyze protein structure such as mass spectrometry or cryo-electron microscopy, cryo-electron tomography enables researchers to observe proteins in their native environment.