these agonists raise HDL but can also raise hepatic triglycerides levels, which might adversely affect HDL function PPARγ agonists (thiazolidinediones) Increase apoA-I synthesis; effective in ...

A small study of Sanofi’s lixisenatide has suggested that the GLP-1 agonist could slow down the progression of Parkinson’s disease, pointing to another potential use for the fast-growing drug ...

And while Musk’s body is in the spotlight now, it’s not the first time he’s admitted to using GLP-1 agonists to manage his weight. In October 2022, he was asked on X what his “secret” to ...

Hilton’s luxury brand to make Hiroshima debut, overlooking the iconic Grand Torii Gate of UNESCO World Heritage Site Itsukushima Shrine… Hilton has announced that an LXR Hotels & Resorts property is ...

What’s the ongoing story: In a first, scientists at the World Health Organisation (WHO) have endorsed a new class of medicines known as GLP-1 receptor agonists, which mimic a hormone that regulates ...

Once thought to be in a terminally differentiated state, macrophages are now understood to be highly pliable, attuned and receptive to environmental cues that control and align responses. In ...

PPAR has made some progress in the treatment of eye diseases: PPARa agonists can inhibit diabetes keratopathy and corneal neuropathy. PPARa agonists inhibit early immature angiogenesis in corneal ...

These findings support the idea that selective agonists of NR2F6 might represent a novel therapeutic strategy in the treatment of certain forms of human IBD, especially as nuclear receptors are ...

Department of Biochemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, Brazil ...