gut.bmj12d
Aspirin is associated with lower risk of pancreatic cancer and cancer-related mortality in patients with diabetes mellitus
Background Patients with type 2 diabetes mellitus (T2DM) have higher pancreatic cancer (PC) risk. While aspirin has chemopreventive effects on digestive cancers, its effect on PC among patients with ...
gut.bmj23d
Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study
Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, ...
gut.bmj2d
Risk of acute arterial events associated with treatment of inflammatory bowel diseases: nationwide French cohort study
Correspondence to Julien Kirchgesner, Service de Gastroentérologie et Nutrition, Hôpital Saint-Antoine, Assistance Publique - Hôpitaux de Paris, 184 rue du faubourg Saint-Antoine, Paris 75012, France; ...
gut.bmj2d
PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis
1 Division of Gastroenterology and Hepatology, Mayo Clinic and Foundation, Rochester, MN, USA 2 Division of Biostatistics, Mayo Clinic and Foundation, Rochester, MN, USA Correspondence to: Dr E V ...
gut.bmj1d
Topical diltiazem and bethanechol decrease anal sphincter pressure without side effects
BACKGROUND Topical nitrates lower anal sphincter pressure and heal anal fissures, but a majority of patients experience headache. The internal anal sphincter has a calcium dependent mechanism to ...
gut.bmj2d
Dietary fibres and IBS: translating functional characteristics to clinical value in the era of personalised medicine
Clinical guidelines in the use of fibre supplementation for patients with IBS provide one-size-fits-all advice, which has limited value. This narrative review addresses data and concepts around the ...
gut.bmj4d
Risk assessment after acute upper gastrointestinal haemorrhage.
The aim of this study was to establish the relative importance of risk factors for mortality after acute upper gastrointestinal haemorrhage, and to formulate a simple numerical scoring system that ...
gut.bmj3d
Alternative treatments for type 2 diabetes and associated metabolic diseases: medical therapy or endoscopic duodenal mucosal remodelling?
Correspondence to Professor Jacques J G H M Bergman, Gastroenterology and Hepatology, Amsterdam UMC Location AMC, Amsterdam 1105 AZ, The Netherlands; j.j.bergman{at}amsterdamumc.nl Despite important ...
gut.bmj5d
Nerve growth factor and Trk high affinity receptor (TrkA) gene expression in inflammatory bowel disease
Dr Helmut Friess, Department of Visceral and Transplantation Surgery, University of Bern, Inselspital, CH-3010 Bern, Switzerland. Email: helmut.friess{at}insel.ch BACKGROUND Nerve growth factor (NGF), ...
gut.bmj5d
Faecal metabolome and its determinants in inflammatory bowel disease
Objective Inflammatory bowel disease (IBD) is a multifactorial immune-mediated inflammatory disease of the intestine, comprising Crohn’s disease and ulcerative colitis. By characterising metabolites ...
gut.bmj7d
Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy
2 Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China Background Tumourigenesis in right-sided and left-sided colons demonstrated ...
gut.bmj1d
Effect of luminal ions on the transepithelial electrical potential difference of human rectum
Skin electrodes are the most convenient reference electrodes for clinical measurements of electrical potential differences (pd) across the epithelium of the ...