The EMBO Journal2d
Hormone circuit explains why most HPA drugs fail for mood disorders and predicts the few that work
A mathematical model suggests that existing HPA-targeting drugs failed in clinical trials for mood disorders because the ...
The EMBO Journal3d
Rapid human oogonia-like cell specification via transcription factor-directed differentiation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This study identifies combinations of TFs that ...
The EMBO Journal4d
High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors
High CDC20 expression promotes aneuploid cancer cell sensitivity to spindle assembly checkpoint (SAC) inhibition by ...
The EMBO Journal5d
Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The DNA-damaging agent Gemcitabine (GEM) is a ...
The EMBO Journal5d
Ephrin A1 functions as a ligand of EGFR to promote EMT and metastasis in gastric cancer
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Distant metastasis is the major cause of ...
The EMBO Journal5d
The Shu complex interacts with the replicative helicase to prevent mutations and aberrant recombination
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Homologous recombination (HR) is important for ...
The EMBO Journal8d
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Disorders of surfactant protein biology cause ...